› 3q0u

X-ray diffraction
1.7Å resolution

EthR from Mycobacterium tuberculosis in complex with compound BDM31379

Released:
DOI: 10.2210/pdb3q0u/pdb
PDB entry 3q0u coloured by chain, front view.
PDB entry 3q0u coloured by chain, side view.
PDB entry 3q0u coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Flipo M, Desroses M, Dirie B, Carette X, Lens Z, Rucktooa P, Leroux F, Piveteau C, Demirkaya F, Locht C, Villeret V, Christophe T, Jeon HK, Brodin P, Deprez B, Baulard A, Willand N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator EthR Chain: A
Molecule details ›
Chain: A
Length: 236 amino acids
Theoretical weight: 25.95 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WMC1 (Residues: 1-216; Coverage: 100%)
Gene names: Rv3855, etaR, ethR
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand LL3 1 x LL3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P41212
Unit cell:
a: 122.17Å b: 122.17Å c: 33.67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.234
Expression system: Escherichia coli

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