3pgd Summary details

pdbe.org/3pgd/summary_details
spacer Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation
Summary
Header IMMUNE SYSTEMsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.72 Å, R-factor: 19.83%, Free R-factor: 24.16%, Spacegroup: P 43 21 2
Released 08/12/2010, deposition: 01/11/2010, last revision: 05/01/2011
Authors Gunther, S.search; Schlundt, A.search; Sticht, J.search; Roske, Y.search; Heinemann, U.search; Wiesmuller, K.-H.search; Jung, G.search; Falk, K.search; Rotzschke, O.search; Freund, C.search
Primary citation Bidirectional binding of invariant chain peptides to an MHC class II molecule.
PROC.NATL.ACAD.SCI.USAsearch vol:107, pag:22219-22224 (2010) [PubMed 21115828 ]search
Keywords MHC class IIsearch, MHC IIsearch, immune systemsearch, self antigensearch, invariant chainsearch, CLIPsearch
Organism Homo sapiens(human) 9606search(A D B E C F)
UniProt P01903search (A D)
P04229search (B E)
P04233search (C F)
Solvent A, B, C, D, E, F
Related entries 3pgc
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, D HLA class II histocompatibility antigen, DR alpha chain Protein P01903 (DRA_HUMAN)search
193 92%
B, E HLA class II histocompatibility antigen, DRB1-1 beta chain Protein P04229 (2B11_HUMAN)search
199 92%
C, F HLA class II histocompatibility antigen gamma chain Protein P04233 (HG2A_HUMAN)search
15 100%
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