3p9s Summary


Structure of I274A variant of E. coli KatE

The structure was published by Jha, V., Louis, S., Chelikani, P., et al., Donald, L.J., Fita, I., and Loewen, P.C., in 2011 in a paper entitled "Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2010.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Catalase HPII.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Catalase HPII P21179 (1-753) (CATE_ECOLI)search Escherichia coli K-12search 100% 753 96%
B Catalase HPII P21179 (1-753) (CATE_ECOLI)search Escherichia coli K-12search 100% 753 96%
C Catalase HPII P21179 (1-753) (CATE_ECOLI)search Escherichia coli K-12search 100% 753 96%
D Catalase HPII P21179 (1-753) (CATE_ECOLI)search Escherichia coli K-12search 100% 753 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P21179 (1 - 753) Catalase HPII Escherichia coli K-12

Chain Sequence family (Pfam)
A, B, C, D (P21179) PF00199: Catalasesearch, PF06628: Catalase-related immune-responsivesearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B, C, D (P21179) catalase activitysearch identical protein bindingsearch peroxidase activitysearch heme bindingsearch metal ion bindingsearch iron ion bindingsearch oxidoreductase activitysearch cytosolsearch cytoplasmsearch cellular response to DNA damage stimulussearch oxidation-reduction processsearch response to oxidative stresssearch hydrogen peroxide catabolic processsearch hyperosmotic responsesearch

Chain InterPro annotation
A, B, C, D Catalase haem-binding sitesearch Catalase immune-responsive domainsearch Catalase core domainsearch Catalase, mono-functional, haem-containingsearch Catalase-like domainsearch Catalase active sitesearch Catalase, mono-functional, haem-containing, clade 2search Class I glutamine amidotransferase-likesearch