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The SECRET domain in complex with CX3CL1

Source organisms:
Biochemical function: chemokine activity
Biological process: immune response
Cellular component: extracellular region

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00048
Domain description: Small cytokines (intecrine/chemokine), interleukin-8 like
Occurring in:
  1. Processed fractalkine
The deposited structure of PDB entry 3ona contains 1 copy of Pfam domain PF00048 (Small cytokines (intecrine/chemokine), interleukin-8 like) in Processed fractalkine. Showing 1 copy in chain B.

PF07190
Domain description: Tumour necrosis factor receptor, SECRET domain
Occurring in:
  1. TNFR-Cys domain-containing protein
The deposited structure of PDB entry 3ona contains 1 copy of Pfam domain PF07190 (Tumour necrosis factor receptor, SECRET domain) in TNFR-Cys domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001811
Domain description: Chemokine interleukin-8-like domain
Occurring in:
  1. Processed fractalkine
IPR036048
Domain description: Chemokine interleukin-8-like superfamily
Occurring in:
  1. Processed fractalkine
IPR039809
Domain description: Chemokine beta/gamma/delta
Occurring in:
  1. Processed fractalkine
IPR034127
Domain description: CX3C chemokine domain
Occurring in:
  1. Processed fractalkine
IPR010806
Domain description: Poxvirus, TNF receptor-II, C-terminal
Occurring in:
  1. TNFR-Cys domain-containing protein

Structure domains

CATH CATH domains
2.40.50.40
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. Processed fractalkine
The deposited structure of PDB entry 3ona contains 1 copy of CATH domain 2.40.50.40 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Processed fractalkine. Showing 1 copy in chain B.
2.60.240.20
Class: Mainly Beta
Architecture: Sandwich
Topology: Viral Chemokine Inhibitor; Chain A
Homology: Viral Chemokine Inhibitor; Chain A
Occurring in:
  1. TNFR-Cys domain-containing protein
The deposited structure of PDB entry 3ona contains 1 copy of CATH domain 2.60.240.20 (Viral Chemokine Inhibitor; Chain A) in TNFR-Cys domain-containing protein. Showing 1 copy in chain A.

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