Assemblies
Assembly Name:
TNFR-Cys domain-containing protein and Processed fractalkine
Multimeric state:
hetero dimer
Accessible surface area:
11864.2 Å2
Buried surface area:
1100.11 Å2
Dissociation area:
550.06
Å2
Dissociation energy (ΔGdiss):
-1.34
kcal/mol
Dissociation entropy (TΔSdiss):
10.55
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-160267
Macromolecules
Chain: A
Length: 163 amino acids
Theoretical weight: 18.01 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
Pfam: Tumour necrosis factor receptor, SECRET domain
InterPro: Poxvirus, TNF receptor-II, C-terminal
CATH: Viral Chemokine Inhibitor; Chain A
Length: 163 amino acids
Theoretical weight: 18.01 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q7TDW8 (Residues: 162-320; Coverage: 50%)
Pfam: Tumour necrosis factor receptor, SECRET domain
InterPro: Poxvirus, TNF receptor-II, C-terminal
CATH: Viral Chemokine Inhibitor; Chain A
Chain: B
Length: 80 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Small cytokines (intecrine/chemokine), interleukin-8 like
InterPro:
Length: 80 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P78423 (Residues: 24-100; Coverage: 20%)
Pfam: Small cytokines (intecrine/chemokine), interleukin-8 like
InterPro:
- CX3C chemokine domain
- Chemokine beta/gamma/delta
- Chemokine interleukin-8-like superfamily
- Chemokine interleukin-8-like domain
