Function and Biology Details
Reaction catalysed:
(1a) NAD(+) = cyclic ADP-ribose + nicotinamide
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-134412 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Interleukin-1 beta
Molecule details ›
Chain: A
Length: 158 amino acids
Theoretical weight: 17.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 158 amino acids
Theoretical weight: 17.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P01584 (Residues: 117-269; Coverage: 57%)
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Interleukin-1 receptor type 2, soluble form
Molecule details ›
Chain: C
Length: 339 amino acids
Theoretical weight: 38.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Length: 339 amino acids
Theoretical weight: 38.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P27930 (Residues: 14-343; Coverage: 86%)
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Interleukin-1 receptor accessory protein
Molecule details ›
Chain: B
Length: 339 amino acids
Theoretical weight: 39.26 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Length: 339 amino acids
Theoretical weight: 39.26 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9NPH3 (Residues: 21-350; Coverage: 60%)
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
