› 3o21

X-ray diffraction
2.2Å resolution

High resolution structure of GluA3 N-terminal domain (NTD)

Released:
DOI: 10.2210/pdb3o21/pdb
PDB entry 3o21 coloured by chain, front view.
PDB entry 3o21 coloured by chain, side view.
PDB entry 3o21 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Dynamics and allosteric potential of the AMPA receptor N-terminal domain.
Sukumaran M, Rossmann M, Shrivastava I, Dutta A, Bahar I, Greger IH
EMBO J 30 972-82 (2011)
PMID: 21317871

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148616 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 389 amino acids
Theoretical weight: 44.96 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P19492 (Residues: 23-403; Coverage: 44%)
Gene names: GluA3, Glur3, Gria3
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
Ligand NAG 9 x NAG
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 98.755Å b: 130.91Å c: 131.085Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.258
Expression system: Homo sapiens

Quick links

Citations

11 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
10 more

7 mentions without citation

Emerging models of glutamate receptor ion channel structure and function.
Mayer ML. (2011)
6 more