› › Structure analysis

Rat COMT in complex with a fluorinated desoxyribose-containing bisubstrate inhibitor avoids hydroxyl group

X-ray diffraction
1.3Å resolution
PDB entry 3nwb coloured by chain, front view.
PDB entry 3nwb coloured by chain, side view.
PDB entry 3nwb coloured by chain, top view.
Source organism: Rattus norvegicus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Catechol O-methyltransferase
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 9445.2 Å2
Buried surface area: 868.86 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149780

Macromolecules

Catechol O-methyltransferase
Chain: A
Length: 221 amino acids
Theoretical weight: 24.77 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P22734 (Residues: 44-264; Coverage: 84%)
Gene name: Comt
Pfam: O-methyltransferase
InterPro:
CATH: Vaccinia Virus protein VP39
Catechol O-methyltransferase in PDB entry 3nwb, assembly 1, front view.
Catechol O-methyltransferase in PDB entry 3nwb, assembly 1, side view.
Catechol O-methyltransferase in PDB entry 3nwb, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links