Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA topoisomerase, type IIA, subunit B
- DNA topoisomerase, type IIA, domain A
- TOPRIM domain
- DNA topoisomerase, type IIA, subunit B, C-terminal
- DNA topoisomerase, type IIA-like domain superfamily
- DNA gyrase B subunit, C-terminal
- DNA gyrase subunit B insert domain
- DNA topoisomerase, type IIA, conserved site
4 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
GyrA-GyrB DNA Gyrase complex (preferred)
PDBe Complex ID:
PDB-CPX-142492 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA gyrase subunit A
Molecule details ›
Chain: A
Length: 525 amino acids
Theoretical weight: 59.66 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
Structure domains:
Length: 525 amino acids
Theoretical weight: 59.66 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P0AES4 (Residues: 1-525; Coverage: 60%)
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
Structure domains:
DNA gyrase subunit B
Molecule details ›
Chain: B
Length: 420 amino acids
Theoretical weight: 48.23 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 420 amino acids
Theoretical weight: 48.23 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P0AES6 (Residues: 389-804; Coverage: 52%)
Sequence domains:
Structure domains:
