High resolution structure of naproxen:COX-2 complex.
The structure was published by Duggan, K.C., Walters, M.J., Musee, J., et al., Kiefer, J.R., Oates, J.A., and Marnett, L.J., in 2010 in a paper entitled "Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.73 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Prostaglandin-endoperoxide synthase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: