EC 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase
Reaction catalysed:
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine
Systematic name:
1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase
Alternative Name(s):
- Lysophospholipase D
GO terms
Biochemical function:
- alkylglycerophosphoethanolamine phosphodiesterase activity
- metal ion binding
- polysaccharide binding
- hydrolase activity, acting on ester bonds
- hydrolase activity
- zinc ion binding
- calcium ion binding
- scavenger receptor activity
- lysophospholipase activity
- dinucleotide phosphatase activity
- phosphodiesterase I activity
- nucleic acid binding
Biological process:
- positive regulation of lamellipodium morphogenesis
- positive regulation of substrate adhesion-dependent cell spreading
- cell chemotaxis
- positive regulation of focal adhesion assembly
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of oligodendrocyte differentiation
- estrous cycle
- phosphatidylcholine catabolic process
- regulation of cell migration
- sphingolipid catabolic process
- vesicle-mediated transport
- lipid catabolic process
- positive regulation of epithelial cell migration
- phospholipid catabolic process
- positive regulation of cell population proliferation
- immune response
- chemotaxis
- phospholipid metabolic process
- lipid metabolic process
- negative regulation of cell-matrix adhesion
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
4.10.410.20
Class:
Few Secondary Structures
Architecture:
Irregular
Topology:
Factor Xa Inhibitor
Homology:
Factor Xa Inhibitor
Occurring in:
3.40.570.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Extracellular Endonuclease; Chain A
Homology:
Extracellular Endonuclease, subunit A
Occurring in:
