› 3ngj

X-ray diffraction
1.7Å resolution

Crystal structure of a putative deoxyribose-phosphate aldolase from Entamoeba histolytica

Released:
DOI: 10.2210/pdb3ngj/pdb
PDB entry 3ngj coloured by chain, front view.
PDB entry 3ngj coloured by chain, side view.
PDB entry 3ngj coloured by chain, top view.
Source organism: Entamoeba histolytica
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111346 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
deoxyribose-phosphate aldolase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 239 amino acids
Theoretical weight: 25.5 KDa
Source organism: Entamoeba histolytica
Expression system: Escherichia coli
UniProt:
  • Canonical: C4M5C6 (Residues: 1-218; Coverage: 100%)
Gene name: EHI_121800
Sequence domains: DeoC/LacD family aldolase
Structure domains: Aldolase class I

Ligands and Environments

3 bound ligands:
Ligand NA 4 x NA
Ligand ZN 8 x ZN
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P21
Unit cell:
a: 50.26Å b: 70.78Å c: 126.75Å
α: 90° β: 92.46° γ: 90°
R-values:
R R work R free
0.147 0.146 0.175
Expression system: Escherichia coli

Quick links