Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain
The structure was published by Yang, H., Wang, J., Du, J., et al., Guo, H., Guo, Y., and Ding, J., in 2010 in a paper entitled "Structural basis of immunosuppression by the therapeutic antibody daclizumab" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.86 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab, and Interleukin-2 receptor subunit alpha.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: