› 3na5

X-ray diffraction
1.7Å resolution

Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of several human pathogens.

Released:
DOI: 10.2210/pdb3na5/pdb
PDB entry 3na5 coloured by chain, front view.
PDB entry 3na5 coloured by chain, side view.
PDB entry 3na5 coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Primary publication:
Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Mehra-Chaudhary R, Mick J, Tanner JJ, Henzl MT, Beamer LJ
Proteins 79 1215-29 (2011)
PMID: 21246636

Function and Biology Details

Reaction catalysed: 
Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187366 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

2 bound ligands:
Ligand BTB 2 x BTB
Ligand MG 2 x MG
1 modified residue:
Ligand CSS 2 x CSS

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P212121
Unit cell:
a: 81.466Å b: 105.792Å c: 126.797Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.218
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Normal Mode Analysis as a Routine Part of a Structural Investigation.
Bauer et al. (2019)
1 more

3 mentions without citation

Biology, Mechanism, and Structure of Enzymes in the α-d-Phosphohexomutase Superfamily.
Stiers et al. (2017)
2 more