Function and Biology Details
Reaction catalysed:
2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H(2)O = ribonucleoside diphosphate + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribonucleotide reductase Class Ib, NrdI
- Ribonucleotide reductase small subunit family
- Flavoprotein-like superfamily
- Ribonucleotide reductase, class Ib, NrdI, bacterial
- Rossmann-like alpha/beta/alpha sandwich fold
- Ribonucleotide reductase small subunit, acitve site
- Ribonucleotide reductase small subunit
- Ribonucleoside-diphosphate reductase subunit beta
2 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141543 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonucleoside-diphosphate reductase 2 subunit beta
Molecule details ›
Chains: A, B
Length: 319 amino acids
Theoretical weight: 36.48 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
Length: 319 amino acids
Theoretical weight: 36.48 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P37146 (Residues: 1-319; Coverage: 100%)
Sequence domains: Ribonucleotide reductase, small chain
Structure domains: Ribonucleotide Reductase, subunit A
Protein NrdI
Molecule details ›
Chains: C, D
Length: 153 amino acids
Theoretical weight: 17.22 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: NrdI Flavodoxin like
Structure domains: Rossmann fold
Length: 153 amino acids
Theoretical weight: 17.22 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A772 (Residues: 1-133; Coverage: 98%)
Sequence domains: NrdI Flavodoxin like
Structure domains: Rossmann fold
