ABL kinase in complex with imatinib and a fragment (FRAG1) in the myristate pocket
The structure was published by Jahnke, W., Grotzfeld, R.M., Pelle, X., et al., Furet, P., Mestan, J., and Marzinzik, A.L., in 2010 in a paper entitled "Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Tyrosine-protein kinase ABL1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: