Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2
The structure was published by Orlicky, S., Tang, X., Neduva, V., et al., Brown, E.D., Sicheri, F., and Tyers, M., in 2010 in a paper entitled "An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Suppressor of kinetochore protein 1 and Cell division control protein 4.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: