› 3m9i

Electron crystallography
2.5Å resolution

Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) in E. coli polar lipids

Released:
DOI: 10.2210/pdb3m9i/pdb
PDB entry 3m9i coloured by chain, front view.
PDB entry 3m9i coloured by chain, side view.
PDB entry 3m9i coloured by chain, top view.
Source organism: Ovis aries
Primary publication:
Principles of membrane protein interactions with annular lipids deduced from aquaporin-0 2D crystals.
Hite RK, Li Z, Walz T
EMBO J 29 1652-8 (2010)
PMID: 20389283

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lens fiber major intrinsic protein Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 23.51 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: Q6J8I9 (Residues: 7-226; Coverage: 84%)
Gene names: AQP0, MIP
Sequence domains: Major intrinsic protein
Structure domains: Glycerol uptake facilitator protein.

Ligands and Environments

1 bound ligand:
Ligand 3PE 7 x 3PE
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.5Å

Quick links

Citations

20 review citations

Emerging Diversity in Lipid-Protein Interactions.
Corradi et al. (2019)
19 more

13 mentions without citation

Tolerance to changes in membrane lipid composition as a selected trait of membrane proteins.
Sanders et al. (2011)
12 more