› 3lm0

X-ray diffraction
2.35Å resolution

Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)

Released:
DOI: 10.2210/pdb3lm0/pdb
PDB entry 3lm0 coloured by chain, front view.
PDB entry 3lm0 coloured by chain, side view.
PDB entry 3lm0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ugochukwu E, Soundararajan M, Rellos P, Fedorov O, Phillips C, Wang J, Hapka E, Filippakopoulos P, Chaikuad A, Pike ACW, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131752 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase 17B Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 37.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O94768 (Residues: 25-329; Coverage: 82%)
Gene names: DRAK2, STK17B
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand EBD 1 x EBD
Ligand EDO 1 x EDO
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P4122
Unit cell:
a: 83.54Å b: 83.54Å c: 115.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.202 0.267
Expression system: Escherichia coli

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