Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
The structure was published by Moulaei, T., Shenoy, S.R., Giomarelli, B., et al., Dauter, Z., O'Keefe, B.R., and Wlodawer, A., in 2010 in a paper entitled "Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 0.97 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Griffithsin. This molecule has the UniProt identifier P84801 (GRFIN_GRISQ). The sample contained 123 residues which is < 90% of the natural sequence. Out of 123 residues 122 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: