3les Summary

pdbe.org/3les
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2F5 Epitope scaffold ES2

The structure was published by Ofek, G., Guenaga, F.J., Schief, W.R., et al., Baker, D., Wyatt, R., and Kwong, P.D., in 2010 in a paper entitled "Elicitation of structure-specific antibodies by epitope scaffolds." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.77 Å and deposited in 2010.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of RNA polymerase sigma factor.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RNA polymerase sigma factor Q9EZJ8 (93-271) (SIGA_THEAQ)search Thermus aquaticussearch 100% 179 100%
B RNA polymerase sigma factor Q9EZJ8 (93-271) (SIGA_THEAQ)search Thermus aquaticussearch 100% 179 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9EZJ8 (93 - 271) RNA polymerase sigma factor Thermus aquaticus

Chain Sequence family (Pfam)
A, B (Q9EZJ8) PF00140: Sigma-70 factor, region 1.2search, PF04542: Sigma-70 region 2search

Chain ID Molecular function (GO) Biological process (GO)
A, B (Q9EZJ8) sigma factor activitysearch sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch DNA-templated transcription, initiationsearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
A, B RNA polymerase sigma-70search RNA polymerase sigma-70 region 2search RNA polymerase sigma factor, region 2search RNA polymerase sigma-70 like domainsearch