Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
The structure was published by Lee, C.C., Jia, Y., Li, N., et al., Lesley, S.A., Harris, J.L., and Spraggon, G., in 2010 in a paper entitled "Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of ALK tyrosine kinase receptor. This molecule has the UniProt identifier Q9UM73 (ALK_HUMAN). The sample contained 344 residues which is < 90% of the natural sequence. Out of 344 residues 307 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: