crystal structure of PKAB3 (pka triple mutant V123A, L173M, Q181K) with compound 27
The structure was published by Zeng, Q., Allen, J.G., Bourbeau, M.P., et al., Dominguez, C., Hungate, R., and Zhang, X., in 2010 in a paper entitled "Azole-based inhibitors of AKT/PKB for the treatment of cancer." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely cAMP-dependent protein kinase catalytic subunit alpha and cAMP-dependent protein kinase inhibitor alpha.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: