spacer Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
CATH: Protein Structure Classification
CATH code 3.10.100.10 search
Domains
3l9jC00
Name Tnfalpha. Chain: c. Engineered: yes. Tumor necrosis factor, soluble form. Chain: t. Fragment: unp residues 85-233. Synonym: tnf-alpha, tumornecrosis factor ligand superfamily member 2, tnf-a, cachectin. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Expression_system_vector_type: plasmid.
Polymers C
Uniprot P05452
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Mannose-Binding Protein A; Chain A search
Homologous superfamily Mannose-Binding Protein A, subunit A search
 
CATH code 2.60.120.40 search
Domains
3l9jT00
Name Tnfalpha. Chain: c. Engineered: yes. Tumor necrosis factor, soluble form. Chain: t. Fragment: unp residues 85-233. Synonym: tnf-alpha, tumornecrosis factor ligand superfamily member 2, tnf-a, cachectin. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Expression_system_vector_type: plasmid.
Polymers T
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Jelly Rolls search
Homologous superfamily Jelly Rolls search
 
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