3l6f Summary details

pdbe.org/3l6f/summary_details
spacer Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1
Summary
Header IMMUNE SYSTEM/PEPTIDE BINDING PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.1 Å, R-factor: 21.17%, Free R-factor: 24.94%, Spacegroup: P 21 21 2
Released 12/05/2010, deposition: 23/12/2009, last revision: 28/07/2010
Authors Li, Y.search; Mariuzza, R.A.search
Primary citation Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4(+) T Cells.
J.MOL.BIOL.search vol:399, pag:596-603 (2010) [PubMed 20417641 ]search
Keywords MHC class IIsearch, HLA-DR1search, phosphopeptidesearch, Disulfide bondsearch, Glycoproteinsearch, Immune responsesearch, Membranesearch, MHC IIsearch, Transmembranesearch, Endoplasmic reticulumsearch, Golgi apparatussearch, IMMUNE SYSTEM-PEPTIDE BINDING PROTEIN complexsearch
Organism Homo sapiens(human) 9606search(A B C)
UniProt P01903search (A)
P04229search (B)
Q16655search (C)
Solvent A, B, C
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A HLA class II histocompatibility antigen, DR alpha chain Protein P01903 (DRA_HUMAN)search
182 97%
B HLA class II histocompatibility antigen, DRB1-1 beta chain Protein P04229 (2B11_HUMAN)search
193 98%
C Melanoma antigen recognized by T-cells 1 Protein Q16655 (MAR1_HUMAN)search
15 100%
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