Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1
The structure was published by Li, Y., Depontieu, F.R., Sidney, J., et al., Sette, A., Topalian, S.L., and Mariuzza, R.A., in 2010 in a paper entitled "Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4(+) T Cells." (abstract).
This crystal structure
was determined using
at a resolution of 2.1 Å and deposited in 2009.
This PDB entry contains a complex of 3 biomacromolecules, namely HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, and Melanoma antigen recognized by T-cells 1.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
Name of source organism
% of UniProt sequence present in the sample
Residues in the sample molecules
% of residues observed
HLA class II histocompatibility antigen, DR alpha chain