Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
- Netrin module, non-TIMP type
- Tissue inhibitor of metalloproteinases-like, OB-fold
- Alpha-macroglobulin, receptor-binding
- Alpha-macroglobulin, receptor-binding domain superfamily
- Immunoglobulin-like fold
- Heat shock protein 70kD, C-terminal domain superfamily
- Staphylococcal complement inhibitor SCIN
- Netrin domain
11 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133834 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C3 beta chain
Molecule details ›
Chain: A
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01024 (Residues: 23-667; Coverage: 39%)
Sequence domains:
Complement C3b alpha' chain
Molecule details ›
Chain: B
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 749-1663; Coverage: 56%)
Sequence domains:
Staphylococcal complement inhibitor
Molecule details ›
Chain: M
Length: 88 amino acids
Theoretical weight: 10.06 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
Sequence domains: Staphylococcal complement inhibitor SCIN
Length: 88 amino acids
Theoretical weight: 10.06 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
- Canonical: Q931M7 (Residues: 32-116; Coverage: 100%)
Sequence domains: Staphylococcal complement inhibitor SCIN
