X-ray crystal structure of arachidonic acid bound in the cyclooxygenase channel of L531F murine COX-2
The structure was published by Vecchio, A.J., Simmons, D.M., and Malkowski, M.G., in 2010 in a paper entitled "Structural basis of fatty acid substrate binding to cyclooxygenase-2." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Prostaglandin G/H synthase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: