3krj

X-ray diffraction
2.1Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-139511 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 1; Macrophage colony-stimulating factor 1 receptor Chain: A
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 38.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P07333 (Residues: 538-678, 686-686, 753-922; Coverage: 33%)
  • Canonical: P11362 (Residues: 577-583, 585-597; Coverage: 3%)
Gene names: BFGFR, CEK, CSF1R, FGFBR, FGFR1, FLG, FLT2, FMS, HBGFR
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: R3
Unit cell:
a: 82.875Å b: 82.875Å c: 144.408Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.208 0.26
Expression system: Spodoptera frugiperda