3kk9 Summary

pdbe.org/3kk9
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CaMKII Substrate Complex B

The structure was published by Chao, L.H., Pellicena, P., Deindl, S., Barclay, L.A., Schulman, H., and Kuriyan, J., in 2010 in a paper entitled "Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.206 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Calcium/calmodulin dependent protein kinase II. This molecule has the UniProt identifier O62305 (KCC2D_CAEEL)search. The sample contained 282 residues which is < 90% of the natural sequence. Out of 282 residues 275 were observed and are deposited in the PDB.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Calcium/calmodulin dependent protein kinase II O62305 (6-287) (KCC2D_CAEEL)search Caenorhabditis eleganssearch < 90% 282 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O62305 (6 - 287) Calcium/calmodulin dependent protein kinase II Caenorhabditis elegans

Chain Structural classification (CATH) Sequence family (Pfam)
A Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (O62305) protein phosphorylationsearch ATP bindingsearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch Calcium/calmodulin-dependent/calcium-dependent protein kinasesearch