› 3khf

X-ray diffraction
1.2Å resolution

The crystal structure of the PDZ domain of human Microtubule Associated Serine/Threonine Kinase 3 (MAST3)

Released:
DOI: 10.2210/pdb3khf/pdb
PDB entry 3khf coloured by chain, front view.
PDB entry 3khf coloured by chain, side view.
PDB entry 3khf coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Roos A, Elkins J, Savitsky P, Wang J, Ugochukwu E, Murray J, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, von Delft F, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-129935 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated serine/threonine-protein kinase 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 99 amino acids
Theoretical weight: 10.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60307 (Residues: 948-1040; Coverage: 7%)
Gene names: KIAA0561, MAST3
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

2 bound ligands:
Ligand EDO 2 x EDO
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 48.65Å b: 55.537Å c: 59.387Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.156 0.171
Expression system: Escherichia coli

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