Assemblies
Assembly Name:
Lysosomal acid glucosylceramidase
Multimeric state:
homo dimer
Accessible surface area:
37762.83 Å2
Buried surface area:
4696.64 Å2
Dissociation area:
363.21
Å2
Dissociation energy (ΔGdiss):
-7.25
kcal/mol
Dissociation entropy (TΔSdiss):
13.87
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-137378
Assembly Name:
Lysosomal acid glucosylceramidase
Multimeric state:
homo dimer
Accessible surface area:
36713.91 Å2
Buried surface area:
5745.47 Å2
Dissociation area:
887.91
Å2
Dissociation energy (ΔGdiss):
6.6
kcal/mol
Dissociation entropy (TΔSdiss):
14.63
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-137378
Assembly Name:
Lysosomal acid glucosylceramidase
Multimeric state:
homo tetramer
Accessible surface area:
71299.9 Å2
Buried surface area:
13618.43 Å2
Dissociation area:
1,039.01
Å2
Dissociation energy (ΔGdiss):
13.89
kcal/mol
Dissociation entropy (TΔSdiss):
15.55
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-137379
Macromolecules
Chains: A, B
Length: 497 amino acids
Theoretical weight: 55.63 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam:
InterPro:
Length: 497 amino acids
Theoretical weight: 55.63 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P04062 (Residues: 40-536; Coverage: 100%)
Pfam:
InterPro:
- Glycoside hydrolase family 30
- Glycosyl hydrolase family 30, TIM-barrel domain
- Glycoside hydrolase superfamily
- Glycosyl hydrolase family 30, beta sandwich domain
