3kb9 Summary

pdbe.org/3kb9
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Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation

The structure was published by Aaron, J.A., Lin, X., Cane, D.E., and Christianson, D.W., in 2010 in a paper entitled "Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.598 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Epi-isozizaene synthase. This molecule has the UniProt identifier Q9K499 (CYC1_STRCO)search. The sample contained 382 residues which is 100% of the natural sequence. Out of 382 residues 340 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Epi-isozizaene synthase Q9K499 (2-361) (CYC1_STRCO)search Streptomyces coelicolor A3(2)search 100% 382 89%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9K499 (2 - 361) Epi-isozizaene synthase Streptomyces coelicolor

Chain Sequence family (Pfam)
A (Q9K499) PF03936: Terpene synthase family, metal binding domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q9K499) terpene synthase activitysearch magnesium ion bindingsearch metal ion bindingsearch epi-isozizaene synthase activitysearch lyase activitysearch metabolic processsearch

Chain InterPro annotation
A Terpene synthase, metal-binding domainsearch Terpenoid synthasesearch