› 3k8j

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130596 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein TP0453 Chain: A
Molecule details ›
Chain: A
Length: 262 amino acids
Theoretical weight: 29.15 KDa
Source organism: Treponema pallidum
Expression system: Escherichia coli
UniProt:
  • Canonical: O67998 (Residues: 27-287; Coverage: 99%)
Gene names: TPANIC_0453, TP_0453
Sequence domains: Outer membrane-associated lipoprotein TP0453

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21212
Unit cell:
a: 45.68Å b: 157.508Å c: 43.019Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.26
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen.
Radolf et al. (2016)
3 more

1 mention without citation

The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.
Luthra et al. (2011)