3k21 Summary


Crystal Structure of carboxy-terminus of PFC0420w.

The structure was published by Wernimont, A.K., Amani, M., Qiu, W., et al., Lew, J., Hutchinson, A., and Hui, R., in 2011 in a paper entitled "Structures of parasitic CDPK domains point to a common mechanism of activation." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.15 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Calcium-dependent protein kinase 3. This molecule has the UniProt identifier Q9NJU9 (CDPK3_PLAF7)search. The sample contained 191 residues which is < 90% of the natural sequence. Out of 191 residues 177 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Calcium-dependent protein kinase 3 Q9NJU9 (388-560) (CDPK3_PLAF7)search Plasmodium falciparum 3D7search < 90% 191 93%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9NJU9 (388 - 560) Calcium-dependent protein kinase 3 Plasmodium falciparum

Chain Structural classification (CATH) Sequence family (Pfam)
A EF-handsearch EF handsearch
Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch