Crystal Structure of TR-beta bound to the selective thyromimetic TRIAC
The structure was published by Martinez, L., Nascimento, A.S., Nunes, F.M., et al., Webb, P., Skaf, M.S., and Polikarpov, I., in 2009 in a paper entitled "Gaining ligand selectivity in thyroid hormone receptors via entropy." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Thyroid hormone receptor beta. This molecule has the UniProt identifier P10828 (THB_HUMAN). The sample contained 263 residues which is < 90% of the natural sequence. Out of 263 residues 244 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: