3j22 Summary

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The Enterovirus 71 A-particle

The structure was published by Shingler, K.L., Yoder, J.L., Carnegie, M.S., et al., Makhov, A.M., Conway, J.F., and Hafenstein, S., in 2013 in a paper entitled "The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating." (abstract).

The structure was determined using Electron microscopy at a resolution of 6.3 Å and deposited in 2012.

The experimental data on which the structure is based was deposited separately in EMDB as entry 5465.

This PDB entry contains a complex of 3 biomacromolecules, namely capsid protein VP1, capsid protein VP0, and capsid protein VP3.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A capsid protein VP1 B2ZUN0 (638-862) (B2ZUN0_9ENTO)search Enterovirus A71search < 90% 225 96%
B capsid protein VP0 B2ZUN0 (82-318) (B2ZUN0_9ENTO)search Enterovirus A71search < 90% 237 100%
C capsid protein VP3 B2ZUN0 (324-562) (B2ZUN0_9ENTO)search Enterovirus A71search < 90% 239 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
B2ZUN0 (638 - 862) capsid protein VP1 Enterovirus A71

Chain Sequence family (Pfam)
A picornavirus capsid proteinsearch
B picornavirus capsid proteinsearch
C picornavirus capsid proteinsearch

Chain ID Cellular component (GO) Molecular function (GO)
A (B2ZUN0) viral capsidsearch structural molecule activitysearch
B (B2ZUN0) viral capsidsearch structural molecule activitysearch
C (B2ZUN0) viral capsidsearch structural molecule activitysearch

Chain InterPro annotation
A Picornavirus capsidsearch Viral coat protein subunitsearch
B Picornavirus capsidsearch Viral coat protein subunitsearch
C Picornavirus capsidsearch Viral coat protein subunitsearch