spacer Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
CATH: Protein Structure Classification
CATH code search
3it8A00 , 3it8B00 , 3it8C00 , 3it8G00 , 3it8H00 , 3it8I00
Name Tumor necrosis factor. Chain: a, b, c, g, h, i. Fragment: tumor necrosis factor, soluble form, unp residues 82-233. Synonym: tnf-alpha, tumor necrosis factor ligand superfamily member 2, tnf-a, cachectin, tumornecrosis factor, membrane form, tumor necrosis factor, soluble form.Engineered: yes. 2l protein. Chain: d, e, f, j, k, l. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: tnf. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_vector_type: plasmid.
Polymers A, B, C, G, H, I
Class Mainly Betasearch
Architecture Sandwich search
Topology Jelly Rolls search
Homologous superfamily Jelly Rolls search