The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
The structure was published by Berger, D.M., Torres, N., Dutia, M., et al., Frommer, E., Wojciechowicz, D., and Mallon, R., in 2009 in a paper entitled "Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.79 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of B-Raf proto-oncogene serine/threonine-protein kinase.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: