3i9q Summary


Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain

The structure was published by Camara-Artigas, A., Andujar-Sanchez, M., Ortiz-Salmeron, E., Cuadri, C., and Casares, S., in 2009 in a paper entitled "The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.45 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Spectrin alpha chain. This molecule has the UniProt identifier P07751 (SPTN1_CHICK)search. The sample contained 57 residues which is < 90% of the natural sequence. Out of 57 residues 56 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Spectrin alpha chain P07751 (969-1025) (SPTN1_CHICK)search Gallus gallussearch < 90% 57 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07751 (969 - 1025) Spectrin alpha chain Gallus gallus

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch, Spectrin repeatsearch

Chain ID Biological process (GO)
A (P07751) endocytosissearch

Chain InterPro annotation
A SH3 domainsearch Spectrin alpha chain, SH3 domainsearch Endophilin-Asearch