3i5s Summary details

pdbe.org/3i5s/summary_details
spacer Crystal structure of PI3K SH3
Summary
Header PROTEIN BINDINGsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 3.0 Å, R-factor: 24.3%, Free R-factor: 29.9%, Spacegroup: P 1 21 1
Released 02/03/2010, deposition: 06/07/2009, last revision: 02/03/2010
Authors Batra-Safferling, R.search; Granzin, J.search; Modder, S.search; Hoffmann, S.search; Willbold, D.search
Primary citation Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding.
BIOL.CHEM.search vol:391, pag:33-42 (2010) [PubMed 19919182 ]search
Keywords SH3 domainsearch, Disease mutationsearch, Host-virus interactionsearch, Phosphoproteinsearch, SH2 domainsearch, PROTEIN BINDINGsearch
Organism Homo sapiens(human) 9606search(A B C D)
UniProt P27986search (A B C D)
Related entries 3i5r
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B, C, D Phosphatidylinositol 3-kinase regulatory subunit alpha Protein P27986 (P85A_HUMAN)search
83 92%
Heterogens
Chain Id Name Ligands
A SULFATE ION SO4 search
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