Crystal structure of c-Met with triazolopyridazine inhibitor 13
The structure was published by Boezio, A.A., Berry, L., Albrecht, B.K., et al., Yang, Y., Zhang, Y., and Harmange, J.C., in 2009 in a paper entitled "Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Hepatocyte growth factor receptor. This molecule has the UniProt identifier P08581 (MET_HUMAN). The sample contained 309 residues which is < 90% of the natural sequence. Out of 309 residues 280 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: