Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor
The structure was published by Aronov, A.M., Tang, Q., Martinez-Botella, G., et al., Straub, J., ter Haar, E., and Xie, X., in 2009 in a paper entitled "Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Glycogen synthase kinase-3 beta.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: