Crystal structure of ustekinumab FAB/IL-12 complex
The structure was published by Luo, J., Wu, S.-J., Lacy, E.R., et al., Heavner, G.A., Richter, H.-T., and Benson, J., in in a paper entitled "Structural Basis For Specificity of Ustekinumab Binding to the p40 Subunit of IL-12 and IL-23" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.0 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This entry contains 9 copies of 4 unique biopolymers (complete list).
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: