3hj3

X-ray diffraction
2.7Å resolution

Crystal Structure of the ChTS-DHFR F207A Non-Active Site Mutant

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-163635 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chain A, crystal structure of Dhfr Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 521 amino acids
Theoretical weight: 60.19 KDa
Source organism: Cryptosporidium hominis
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3221
Unit cell:
a: 121.86Å b: 121.86Å c: 342.352Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.274
Expression system: Escherichia coli