3hgb Summary


Crystal structure of glycine cleavage system protein H from Mycobacterium tuberculosis

The structure was published by Abendroth, J., McCormick, M.S., Edwards, T.E., et al., Kuhn, P., Ruth, R.D., and Stewart, L.J., in 2010 in a paper entitled "X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.75 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Glycine cleavage system H protein. This molecule has the UniProt identifier P9WN55 (GCSH_MYCTU)search. The sample contained 155 residues which is 100% of the natural sequence. Out of 155 residues 132 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glycine cleavage system H protein P9WN55 (1-134) (GCSH_MYCTU)search Mycobacterium tuberculosis H37Rvsearch 99% 155 86%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P9WN55 (1 - 134) Glycine cleavage system H protein Mycobacterium tuberculosis H37Rv

Chain Structural classification (CATH)
A (P9WN55) OB fold (Dihydrolipoamide Acetyltransferase, E2P)search

Chain ID Cellular component (GO) Biological process (GO)
A (P9WN55) glycine cleavage complexsearch glycine decarboxylation via glycine cleavage systemsearch

Chain InterPro annotation
A Glycine cleavage system H-proteinsearch 2-oxo acid dehydrogenase, lipoyl-binding sitesearch Single hybrid motifsearch Glycine cleavage system H-protein, subgroupsearch