3hfp Summary

pdbe.org/3hfp
spacer

Crystal structure of teh complex between CA II and the activator MAI

A publication describing this structure is not available. The depositing authors are Temperini, C.search; Supuran, C.T.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.098 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Carbonic anhydrase 2. This molecule has the UniProt identifier P00918 (CAH2_HUMAN)search. The sample contained 260 residues which is 100% of the natural sequence. Out of 260 residues 256 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Carbonic anhydrase 2 P00918 (1-260) (CAH2_HUMAN)search Homo sapienssearch 98% 260 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00918 (1 - 260) Carbonic anhydrase 2 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A (P00918) Carbonic Anhydrase IIsearch PF00194: Eukaryotic-type carbonic anhydrasesearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P00918) apical part of cellsearch basolateral plasma membranesearch cytoplasmsearch extracellular spacesearch microvillussearch plasma membranesearch cytosolsearch axonsearch membranesearch metal ion bindingsearch carbonate dehydratase activitysearch zinc ion bindingsearch lyase activitysearch protein bindingsearch angiotensin-mediated signaling pathwaysearch bicarbonate transportsearch response to pHsearch response to stresssearch one-carbon metabolic processsearch carbon dioxide transportsearch positive regulation of cellular pH reductionsearch morphogenesis of an epitheliumsearch kidney developmentsearch response to steroid hormone stimulussearch regulation of anion transportsearch regulation of intracellular pHsearch response to organic substancesearch positive regulation of dipeptide transmembrane transportsearch positive regulation of bone resorptionsearch secretionsearch positive regulation of osteoclast differentiationsearch response to estrogen stimulussearch response to zinc ionsearch odontogenesis of dentin-containing toothsearch small molecule metabolic processsearch

Chain InterPro annotation
A Alpha carbonic anhydrasesearch Carbonic anhydrase, alpha-class, conserved sitesearch Carbonic anhydrase 2/13search Carbonic anhydrase, alpha-classsearch