Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2
The structure was published by Hammond, M., Washburn, D.G., Hoang, H.T., et al., Laping, N.J., Schnackenberg, C.G., and Thompson, S.K., in 2009 in a paper entitled "Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Serine/threonine-protein kinase Sgk1. This molecule has the UniProt identifier O00141 (SGK1_HUMAN). The sample contained 373 residues which is < 90% of the natural sequence. Out of 373 residues 275 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: