3hd6 Summary


Crystal Structure of the Human Rhesus Glycoprotein RhCG

The structure was published by Gruswitz, F., Chaudhary, S., Ho, J.D., et al., Sali, A., Westhoff, C.M., and Stroud, R.M., in 2010 in a paper entitled "Function of human Rh based on structure of RhCG at 2.1 A." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Ammonium transporter Rh type C. This molecule has the UniProt identifier Q9UBD6 (RHCG_HUMAN)search. The sample contained 490 residues which is 100% of the natural sequence. Out of 490 residues 403 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Ammonium transporter Rh type C Q9UBD6 (2-479) (RHCG_HUMAN)search Homo sapienssearch 100% 490 82%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9UBD6 (2 - 479) Ammonium transporter Rh type C Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A (Q9UBD6) Ammonium transporter AmtB like domainssearch PF00909: Ammonium Transporter Familysearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A (Q9UBD6) cytoplasmic vesiclesearch extracellular vesicular exosomesearch plasma membranesearch integral component of membranesearch basolateral plasma membranesearch apical plasma membranesearch membranesearch integral component of plasma membranesearch transmembrane transportsearch ammonium transportsearch homeostatic processsearch amine transportsearch ammonium transmembrane transportsearch transportsearch transepithelial ammonium transportsearch regulation of pHsearch cellular ion homeostasissearch epithelial cell differentiationsearch ammonium transmembrane transporter activitysearch ankyrin bindingsearch

Chain InterPro annotation
A Blood group Rhesus C/E/D polypeptidesearch Ammonium transporter AmtB-like domainsearch Ammonium/urea transportersearch