Crystal structure of aurora A in complex with TPX2 and compound 10
The structure was published by Clark, M.A., Acharya, R.A., Arico-Muendel, C.C., et al., Yao, G., Zhao, B., and Morgan, B.A., in 2009 in a paper entitled "Design, synthesis and selection of DNA-encoded small-molecule libraries." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.36 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Serine/threonine-protein kinase 6 and Targeting protein for Xklp2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: